Genyous' goal is to reduce mortality due to cancer and other chronic diseases and to improve quality of life for patients.
Genyous Biomed International ("Genyous") has invented a Multifunctional Multitargeted (MFMT™) drug development platform (patent pending) to create multivalent therapies for early intervention and treatment of heterogeneous chronic diseases such as cancer.
MFMT therapies were developed based on a systems biology strategy that addresses crosstalk between cells, the microenvironment and the host immune response. MFMT therapies are designed to help support biological processes that are key to maintaining homeostasis and managing many chronic diseases. MFMT therapies are designed create an environment in which the body’s immune system, and other forms of intervention, can be more effective. Key therapeutic effects of MFMT therapies include:
- Anti-Viral
- Anti-Oxidative
- Anti-Inflammatory
- Immune Modulating
The Company’s lead MFMT cancer drug candidate, Aneustat™ (OMN54), has received regulatory approval to commence a Phase I clinical trial. The initial focus for Aneustat is lung and prostate cancers. Based on pre-clinical studies, Aneustat has demonstrated significant anti-cancer activity (on par with combination chemotherapy) but without any side effects. Given its wide dosing window, Aneustat is poised for ubiquitous use -- enhancing the efficacy of other therapies (surgery, chemo, radiation) while reducing the toxicity burden for patients.
Genyous anticipates that its MFMT therapies will contribute to the treatment of other solid tumors and related chronic diseases (such as CNS, pain, COPD, prostate disorders such as BPH and Prostatitis) which share many biological pathways and are correlated with increased risk of cancer.
Genyous commercializes its MFMT drug candidates via licensing agreements with its affiliates (Omnitura Therapeutics and Vitala Therapeutics) and other pharmaceutical companies. The Company is currently seeking alliances for commercialization and joint development.
Systems Biology (n.) — The study of biological systems taking into account the interactions of the key elements such as genes, DNA, RNA, proteins, and cells with respect to one another within the cell, its microenvironment, and the host.
Multifunctional Multitargeted (MFMT™) Therapy (n.) — a drug that possesses multiple therapeutic functions and acts upon multiple biological targets to treat chronic diseases.